Leading trade names with dosage forms are given. Important points are summarized in boxes. Infrequently used drugs and those not available in India are described briefly in extract type.
Some other topics added are drug transporters, pharmacogenomics, pharmacovigilance, expiry date of pharmaceuticals, single enantiomer drugs, biological response modifiers, prescribing in pregnancy, etc. Another new chapter compiles the clinically important drug interactions. A chapter is devoted to the principles of ‘rational use of medicines’, elements of ‘evidence based medicine’ and the process of ‘new drug development’ to reflect current importance of these topics. Recent developments have been highlighted, notably in hormone replacement therapy, aromatase inhibitors, bisphosphonates, selective COX-2 inhibitors, atypical antipsychotics, therapy of diabetes mellitus, heart failure, acute coronary syndromes, Alzheimer’s disease, parkinsonism, glaucoma, kala azar, etc. Latest therapeutic guidelines from leading professional bodies, WHO and National Health Programmes have been incorporated, especially in areas like hypertension, hyperlipidaemias, stroke prevention, surgical prophylaxis, tuberculosis, leprosy, malaria, and HIV-AIDS. All chapters have been updated to include recently introduced drugs and published information.
The present edition is oriented to reflect the contemporary advancements. It encompasses all aspects of knowledge about drugs, but most importantly those that are relevant to effective and safe use for medicinal purposes.This book is designed to be useful both to the uninitiated medical student, as well as to prescribing physicians.
In a broad sense, it deals with interaction of exo-genously administered chemical molecules with living systems, or any single chemical substance which can produce a biological response is a ‘drug’. Pharmacology is the science of drugs (Greek: Pharmacon-drug logos-discourse in). The present edition endeavours to amalgamate the developments with the core content of the subject. These efforts have begun to crystallize into evidence based medicine and clear cut therapeutic guidelines. Medical pharmacology is a unique synthesis of basic pharmacology with clinical pharmacology and pharmacotherapeutics.ĭevelopments are occurring both in defining molecular targets for drug action and finding targeted drugs, as well as in accruing credible evidence regarding the impact of different treatment modalities on therapeutic outcomes.
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